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Spicy Sauce for Sandwiches

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This 5-ingredient spicy sauce is the perfect sandwich spread for a grilled reuben but makes a delicious dip for shrimp, too. Stir it together in just a minute and keep it handy in the fridge for dozens of uses.

A mason jar of homemade spicy sauce in front of sliced bread.

I look forward to making my favorite grilled turkey reubens for St. Patrick's Day every spring.

Normally, I use prepared Thousand Island dressing for the sauce but I finally found the perfect homemade spicy sauce substitute.

Made with just 5 ingredients you likely already have on hand, this creamy sandwich spread also makes a delicious dip for shrimp.

The best part? You can adjust the cayenne pepper to make it as mild or as spicy as you prefer!

Jump to:

Ingredients

The ingredients to make homemade spicy sauce is on the counter.

You likely have all of these easy ingredients on hand in your fridge or pantry:

  • Mayonnaise: I used one made with olive oil so it is lighter, but you can use whichever mayo you prefer.
  • Ketchup
  • Prepared Horseradish: Not horseradish sauce, just plain horseradish. I found ours in the seafood department at our grocery store.
  • Cayenne Pepper
  • Sugar

5-Minute Prep

This recipe couldn't be easier. Simply add the ingredients to a small mixing bowl and stir them together!

The ingredients for the spicy sauce are in the mixing bowl.

If you're nervous about the cayenne pepper, start with just a dash and taste it. You can always add a little more if you want it spicier.

The creamy sauce has been stirred together.

Look at that gorgeous creamy pink sandwich spread!

I love it on my favorite turkey reuben but it would be delicious with any sandwich made with roast beef, ham, or veggies!

A sandwich board has a jar of spicy sauce in a mason jar.

Serving Suggestions

This spicy sauce is perfect spreading on a sandwich but you could use it as an appetizer dip like with these boudin balls.

Here are a few of my favorite pairings:

📖 Recipe

A mason jar of homemade spicy sauce in front of sliced bread.

Spicy Sauce

5 from 1 vote
This creamy, spicy sauce is the perfect sandwich spread for a grilled rueben. It also makes an excellent dip or drizzle for shrimp.
TOTAL TIME 5 minutes
PREP TIME 5 minutes
YIELD 2 cups of sauce

Ingredients
  

  • 1/2 cup mayonnaise
  • 1/3 cup ketchup
  • 1 tablespoon prepared horseradish
  • 1/2 teaspoon sugar
  • 1/4 teaspoon cayenne pepper

Instructions

  • Stir together all the ingredients in a small mixing bowl.
  • Store in an airtight container in the fridge for up to one week.
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A photo collage shows the spicy sauce in a mixing bowl and on a sandwich prep board.

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