Home ยป Recipes ยป Pantry

Spicy Sauce for Sandwiches

This post contains links to affiliate websites, such as Amazon, and we receive an affiliate commission for any purchases made by you using these links. We appreciate your support!

This 5-ingredient spicy sauce is the perfect sandwich spread for a grilled reuben but makes a delicious dip for shrimp, too. Stir it together in just a minute and keep it handy in the fridge for dozens of uses.

A mason jar of homemade spicy sauce in front of sliced bread.

I look forward to making my favorite grilled turkey reubens for St. Patrick's Day every spring.

Normally, I use prepared Thousand Island dressing for the sauce but I finally found the perfect homemade spicy sauce substitute.

Made with just 5 ingredients you likely already have on hand, this creamy sandwich spread also makes a delicious dip for shrimp.

The best part? You can adjust the cayenne pepper to make it as mild or as spicy as you prefer!

Jump to:


The ingredients to make homemade spicy sauce is on the counter.

You likely have all of these easy ingredients on hand in your fridge or pantry:

  • Mayonnaise: I used one made with olive oil so it is lighter, but you can use whichever mayo you prefer.
  • Ketchup
  • Prepared Horseradish: Not horseradish sauce, just plain horseradish. I found ours in the seafood department at our grocery store.
  • Cayenne Pepper
  • Sugar

5-Minute Prep

This recipe couldn't be easier. Simply add the ingredients to a small mixing bowl and stir them together!

The ingredients for the spicy sauce are in the mixing bowl.

If you're nervous about the cayenne pepper, start with just a dash and taste it. You can always add a little more if you want it spicier.

The creamy sauce has been stirred together.

Look at that gorgeous creamy pink sandwich spread!

I love it on my favorite turkey reuben but it would be delicious with any sandwich made with roast beef, ham, or veggies!

A sandwich board has a jar of spicy sauce in a mason jar.

Serving Suggestions

This spicy sauce is perfect spreading on a sandwich but you could use it as an appetizer dip like with these boudin balls.

Here are a few of my favorite pairings:

๐Ÿ“– Recipe

A mason jar of homemade spicy sauce in front of sliced bread.

Spicy Sauce

5 from 1 vote
This creamy, spicy sauce is the perfect sandwich spread for a grilled rueben. It also makes an excellent dip or drizzle for shrimp.
TOTAL TIME 5 minutes
PREP TIME 5 minutes
YIELD 2 cups of sauce


  • 1/2 cup mayonnaise
  • 1/3 cup ketchup
  • 1 tablespoon prepared horseradish
  • 1/2 teaspoon sugar
  • 1/4 teaspoon cayenne pepper


  • Stir together all the ingredients in a small mixing bowl.
  • Store in an airtight container in the fridge for up to one week.

Save This Recipe to Your Recipe Box

Find this delicious recipe next time you visit by saving it to your very own recipe box on my site. All your favorites stored in one easy place!

A photo collage shows the spicy sauce in a mixing bowl and on a sandwich prep board.

Share Your Thoughts

Your email address will not be published. Required fields are marked *

Recipe Rating